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It leads to a significant increase in postprandial GLP-1 and PYY concentrations in humans and animal models (Jrgensen et al., 2012

Acute injuries may benefit from 400-500 mcg daily for the first 2-4 weeks, then reducing to maintenance doses

This process is marked by chronic low-grade inflammation (inflammaging), diminished adaptive immunity, and a skewed CD4+/CD8+ T cell ratio, leaving older adults more vulnerable to infection, cancer, and poor vaccine responses [47]

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[DOI] [PubMed] [Google Scholar] Sever M, Klicek R, Radic B, et al